BIO405/505

ADVANCED CELL AND DEVELOPMENTAL BIOLOGY II

Spring 2009

Lectures: Tuesday and Thursday 9:00 to 10:50 in NSC 216

Credit: 4 hours


Faculty:

Dr. Ronald Berezney - Cooke 637 (Course Coordinator)

Dr. James O. Berry - Dorsheimer 107A

Dr. Mary Bisson - Hochstetter 623

Dr. Paul Cullen - Cooke 625


Textbook:
Most of the reading assignments during the course will be from review articles and research journal articles. The textbooks “Cell and Molecular Biology” by Karp and “Molecular Biology of the Cell” by Alberts et al. were used as the textbooks in the Fall semester Advanced Cell and Developmental Biology course (Bio 402/502) and are recommended as reference books for this course.

Grades:
Most of the reading assignments during the course will be from review articles and research journal articles. The textbooks “Cell and Molecular Biology” by Karp and “Molecular Biology of the Cell” by Alberts et al. were used as the textbooks in the Fall semester Advanced Cell and Developmental Biology course (Bio 402/502) and are recommended as reference books for this course.


Advanced Cell and Developmental Biology
Course Outline

Section 1 (Dr. Cullen – 7 Lectures) 1/13 to 2/3

Dr. Cullen's Lectures and Powerpoint Slides
1.     Functional Consequences of Protein Modification (1 lect)
2.    Cell-Surface Adhesion and Variation (1 lect)
3.    Signal Transduction Pathways (1 lect)
4.    Regulated Protein Degradation and the Proteasome  (1 lect)
5.    Genetic and Protein Interaction Networks (1 lect)
6.    Cell Polarity and Morphogenesis  (1 lect)
7.    Cell-Cycle Control  (1 lect)
 

Section 2 (Dr. Berry – 7 Lectures) 2/5 To 2/26

1.    Plant/Pathogens Interactions (3 lectures)
2.    RNAi  (2 lectures)
3.    microRNAs (2 lectures)

Section 3 (Dr. Bisson – 7 Lectures) 3/3 To 3/31
Dr. Bisson's Lecture Material Page
1.     Membrane Properties and Transport Phenomenom
2.    Active and Passive Transport
3.    Bioenergetics
4.    Structure and Function of Transport Proteins
 

Section 4 (Dr. Berezney – 7 Lectures) 4/2 To 4/23

Articles
1.   Nuclear Organization and Genomic Function; Nuclear Lamin Proteins (1 lecture)
2.   Nuclear Import/Export (1 lecture)
3.   DNA Replication/Transcription/RNA Splicing (1 lecture)
4.   Nuclear Matrix Proteins and Nuclear Targeting (1/1/2 lecture)
5.   Nuclear Matrix Proteins and Nuclear Targeting (continued);
  The Nucleolus: rRNA Gene Organization and Function (1/2 lecture)
6.   Dynamics of Genomic Organization & Function in Living Cells (2 lectures)
  Lecture 6 - Lecture 7

End