Bio 402/502
Advanced Cell & Developmental Biology I
Fall, 2010
Section I Syllabus; Lectures 1-10
Dr. Berezney (August 30 - September 22)
Readings (pp) |
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Date |
Topics |
Karp |
Albert |
| Lect 1-3 [8/30; 9/1, 3] | Cell Biology Methods | 5th 5th1-24;459-62;515-18;523-24;727-76 6th 1-24; 448-452;505-08;513-14;715-765 |
1-42;495-497;501-576 579-613 |
| Lect 4: [9/8] | Membrane Structure & Dynamics | 5th 120 - 143 6th 117-140 |
617-646 |
| Lect 5-6: [9/10,13] | Electron Transport & Oxidative Phosphorylation | 5th 179 - 206 6th 173-199 |
813-838 |
| Lect 7: [9/15] | Cell Surface Receptors and Signal Transduction | Chapter 15 | Chapter 15 |
| Lect 8: [9/17] | G-Protein Linked Cell Surface Receptors | Chapter 15 | Chapter 15 |
| Lect 9/10: [9/20,22] | Protein Kinase-Linked Cell Surface Receptors | Chapter 15 | Chapter 15 |
Exam 1 (Tuesday, September 29 )
Office hours: Cooke 637, Tues/Weds 4-5 pm or by appointment. e-mail: berezney@buffalo.edu
• Chapters 2 & 3 of Karp contain background biochemistry of chemical bonding, carbohydrates, lipids, proteins and nucleic acids, bioenergetics and enzyme properties. Similar topics are found in Alberts in Chapters 2 & 3 and in other chapters for nucleic acids. All students in this course should be familiar with this basic biochemistry. Please read these chapters to insure your knowledge and to determine if you have a significant deficit in your biochemical background. If so, please see Dr. Berezney as soon as possible. It will be very difficult to do well in this course without a good understanding of this biochemistry.
• The powerpoint lecture slides for Dr. Berezney’s lectures can be downloaded from our Department website. Click on courses to Bio 402 or 502. Other instructors will post their presentations here or at other informed locations.
Section IV Syllabus; Lectures 1-10
Dr. Berezney (November 15th - December 10th)
Date |
Topics |
Readings Readings [Karp 5th/6th & others]* |
(Karp is a large Powerpoint file consisting of 86 pages which has been broken down into five parts) |
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| Lect 1 [11/15] | Cell Nucleus and its Genome | Karp, p.402-411/393-402; 491-509/481-499 |
| Lect 2 [11/17] | Nuclear Envelope, NPC, Nucleolus & Nuclear Matrix | Karp 437-441; 428-432; 485-489/ 475-479; 507-509/497-499; Lodish, Chapt.13, p. 510-12; Berezney et al, 1995, p. 1-39 |
| Lect 3/4 [11/19 & 22] | Replication / Transcription / RNA Splicing | Karp 444-450/434-440; 556-562/546-552 Berezney et al.,1995, p. 39-54 Berezney, 2002; Ma et al., 1998 |
| Lect 5/6 [11/29 & 12/1] | Nuclear Import / Export & Targeting | Karp 488-491/477-481; Lodish, 426-435 |
| Lect 7-10 [12/3, 6, 8, and 10] | Cell Cycle Regulation & Cancer | Karp 570-579/560-569; 590/580; 662-682/650-671 Lodish, Chapter 13 |
Exam 4 (Thursday , December 16th , 11:45-1:45 pm. in Knox 109)
>> NOTE ROOM CHANGE! <<
*All readings will be placed on the Bio 402/502 website under “Dr. Berezney’s Lectures”
Office hours: Cooke 637, Mon/Weds 4-5 pm or by appointment. e-mail: berezney@buffalo.edu
