Bio 367

DEVELOPMENTAL BIOLOGY


Spring 2008

Lectures given on MWF 10:00-10:50
NSC 215

3 Credit Hours


Instructors:

Dr. Denise Ferkey C353 (Course Coordinator)
Dr. James O. Berry - D 107


Office Hours:
Instructors will establish office hours during the time they are teaching.


Textbook:
“Developmental Biology” by Scott Gilbert (8th edition)
Sinauer Associates Inc., ISBN 0-87893-250-X
The accompanying website (www.devbio.com) can also be searched by topic.
Some additional materials may be provided as handouts.


Exams:
There will be three exams given in this course. These will be given in the evening of February 20th (7pm, NSC 201), the evening of April 3rd (7pm, Knox 110), and during the final exam week. If you have a conflict with one of the exam times, you must inform the instructor immediately. If you miss an exam due to illness, you must present a signed doctor’s note in order to make-up the exam. Rescheduled exams will be handled on a case-by-case basis and may be given as oral exams.

While the third exam will not be a cumulative final, be aware that material covered for the third exam will build on topics presented throughout the course.

Grading:
Grades in this course will be determined on the basis of the three exams, which will be 100 points each. (Your final grade will be based on 300 total points possible.) The final grades will be assigned using the +/- grading system.

Questions regarding grading of an exam must be submitted in writing to the instructor giving the exam within one week from the time the graded exams are returned to the students. The student must check the grading key before asking for a regrade. Note that when a regrade is requested, the entire exam may be regraded.

Academic dishonesty, in any form, will not be tolerated. Cheating on an examination will result in an “F” grade for the entire course and a notation in the departmental file and/or University file that the failing grade was assigned as a result of dishonesty.


Tentative Lecture Schedule

Date

(Dr. Ferkey)

Readings in Gilbert (TBD)
  Background and Introduction  
Jan. 12 Intro to Developmental Biology Chapter 1 (pages: 3-10, 17-19)
Jan. 14 Intro to Developmental Biology Chapter 6 (pages: 139-140, 142-146, 153-154, 160-161)
Jan 16 Intro to Developmental Biology (movie: “A Dozen Eggs”)  
Jan. 19 NO CLASS – Martin Luther King Day  
  Early Events  
Jan. 21 Gametogenesis Chapter 19 (pages: 593-595,
598-602, 605-616, 620-622)
Jan. 23 Fertilization Chapter 7
Jan. 26 Cleavage and Cell Cycle Control Chapter 8 (pages 212-216)
Jan. 28 Cell Adhesion, Extracellular Matrix Chapter 3 (pages 67-74),
Chapter 6 (pages 164-166)
  Development in Selected Invertebrates  
Jan. 30 Sea Urchin Chapter 8 (pages 217-229)
Feb. 2 C. elegans Chapter 8 (pages 243-251)
Feb. 4 C. elegans Chapter 6 (pages 162-164)
Feb. 6 C. elegans  
Feb. 9 Drosophila Chapter 9
Feb. 11 Drosophila  
Feb. 13

Drosophila

 
  (end of material for 1st exam)  
  Development of Selected Vertebrates  
Feb. 16 Xenopus Chapter 10 (pages 291-313)
Feb. 18 Xenopus  
Feb. 20 Xenopus (movie: “From Egg to Tadpole”)  
  (EXAM 1, Dr. Ferkey)  
Feb. 23 Chick (Neurulation) Chapter 12 (pages 373-385)
Feb. 25 Chick (Somitogenesis & Neural Crest) Chapter 14 (pages 444-451)
Chapter 13 (pages 407-413)
Feb. 27 Limb Development Chapter 16 (pages 505-523)
Mar. 2 Cancer – Mutations in Development and Apoptosis  
  Instructor: Dr. Berry  
Mar. 4 DNA methylation, dosage compensation, genomic imprinting TBD
Mar. 6 DNA methylation, dosage compensation, genomic imprinting  
Mar. 9-13 Spring Recess - No Class  
Mar. 16 transcription during development  
Mar. 18 transcription during development  
Mar. 20 RNA splicing and development (Drosophila sex determination)  
Mar. 23 Post-transcriptional control, maternal/zygotic transition  
Mar. 25 RNAi and microRNA regulation of development  
  (end of material for 2nd exam)  
Mar. 27 cDNA and genomics  
Mar. 30 cDNA and genomics  
Apr. 1 Plant life cycles  
Apr. 3 meristem/floral induction  
  (EXAM 2, Dr. Ferkey and Dr. Berry)  
Apr. 6 meristem/floral induction (plant homeotic mutations)  
Apr. 8 growth control/hormones  
Apr. 10 growth control/hormones  
Apr. 13 Agrobacterium and crown gall disease  
Apr. 15 Plant tissue culture/regeneration/genetic engineering  
Apr. 17 Plant tissue culture/regeneration/genetic engineering  
Apr. 20 plastid development  
Apr. 22 environmentally controlled developmental processes in plants and animals  
Apr. 24 environmentally controlled developmental processes in plants and animals  
Apr. 27 environmentally controlled developmental processes in plants and animals  
  (EXAM 3, Dr. Berry, to be scheduled during finals week)  

End