Bio 367
DEVELOPMENTAL BIOLOGY
Spring 2008
Lectures given on MWF
10:00-10:50
NSC 215
3 Credit Hours
Instructors:
Dr. Denise Ferkey C353 (Course Coordinator)
Dr. James O. Berry - D 107
Office Hours:
Instructors will establish office hours during the time they are teaching.
Textbook:
“Developmental Biology” by Scott Gilbert (8th edition)
Sinauer Associates Inc., ISBN 0-87893-250-X
The accompanying website (www.devbio.com) can also be searched by topic.
Some additional materials may be provided as handouts.
Exams:
There will be three exams given in this course. These will be given in the evening of February 20th (7pm, NSC 201), the evening of April 3rd (7pm, Knox 110), and during the final exam week. If you have a conflict with one of the exam times, you must inform the instructor immediately. If you miss an exam due to illness, you must present a signed doctor’s note in order to make-up the exam. Rescheduled exams will be handled on a case-by-case basis and may be given as oral exams.
While the third exam will not be a cumulative final, be aware that material covered for the third exam will build on topics presented throughout the course.
Grading:
Grades in this course will be determined on the basis of the three exams, which will be 100 points each. (Your final grade will be based on 300 total points possible.) The final grades will be assigned using the +/- grading system.
Questions regarding grading of an exam must be submitted in writing to the instructor giving the exam within one week from the time the graded exams are returned to the students. The student must check the grading key before asking for a regrade. Note that when a regrade is requested, the entire exam may be regraded.
Academic dishonesty, in any form, will not be tolerated. Cheating on an examination will result in an “F” grade for the entire course and a notation in the departmental file and/or University file that the failing grade was assigned as a result of dishonesty.
Tentative Lecture Schedule
Date |
(Dr. Ferkey) |
Readings in Gilbert (TBD) |
| Background and Introduction | ||
| Jan. 12 | Intro to Developmental Biology | Chapter 1 (pages: 3-10, 17-19) |
| Jan. 14 | Intro to Developmental Biology | Chapter 6 (pages: 139-140, 142-146, 153-154, 160-161) |
| Jan 16 | Intro to Developmental Biology (movie: “A Dozen Eggs”) | |
| Jan. 19 | NO CLASS – Martin Luther King Day | |
| Early Events | ||
| Jan. 21 | Gametogenesis | Chapter 19 (pages: 593-595, 598-602, 605-616, 620-622) |
| Jan. 23 | Fertilization | Chapter 7 |
| Jan. 26 | Cleavage and Cell Cycle Control | Chapter 8 (pages 212-216) |
| Jan. 28 | Cell Adhesion, Extracellular Matrix | Chapter 3 (pages 67-74), Chapter 6 (pages 164-166) |
| Development in Selected Invertebrates | ||
| Jan. 30 | Sea Urchin | Chapter 8 (pages 217-229) |
| Feb. 2 | C. elegans | Chapter 8 (pages 243-251) |
| Feb. 4 | C. elegans | Chapter 6 (pages 162-164) |
| Feb. 6 | C. elegans | |
| Feb. 9 | Drosophila | Chapter 9 |
| Feb. 11 | Drosophila | |
| Feb. 13 | Drosophila |
|
| (end of material for 1st exam) | ||
| Development of Selected Vertebrates | ||
| Feb. 16 | Xenopus | Chapter 10 (pages 291-313) |
| Feb. 18 | Xenopus | |
| Feb. 20 | Xenopus (movie: “From Egg to Tadpole”) | |
| (EXAM 1, Dr. Ferkey) | ||
| Feb. 23 | Chick (Neurulation) | Chapter 12 (pages 373-385) |
| Feb. 25 | Chick (Somitogenesis & Neural Crest) | Chapter 14 (pages 444-451) Chapter 13 (pages 407-413) |
| Feb. 27 | Limb Development | Chapter 16 (pages 505-523) |
| Mar. 2 | Cancer – Mutations in Development and Apoptosis | |
| Instructor: Dr. Berry | ||
| Mar. 4 | DNA methylation, dosage compensation, genomic imprinting | TBD |
| Mar. 6 | DNA methylation, dosage compensation, genomic imprinting | |
| Mar. 9-13 | Spring Recess - No Class | |
| Mar. 16 | transcription during development | |
| Mar. 18 | transcription during development | |
| Mar. 20 | RNA splicing and development (Drosophila sex determination) | |
| Mar. 23 | Post-transcriptional control, maternal/zygotic transition | |
| Mar. 25 | RNAi and microRNA regulation of development | |
| (end of material for 2nd exam) | ||
| Mar. 27 | cDNA and genomics | |
| Mar. 30 | cDNA and genomics | |
| Apr. 1 | Plant life cycles | |
| Apr. 3 | meristem/floral induction | |
| (EXAM 2, Dr. Ferkey and Dr. Berry) | ||
| Apr. 6 | meristem/floral induction (plant homeotic mutations) | |
| Apr. 8 | growth control/hormones | |
| Apr. 10 | growth control/hormones | |
| Apr. 13 | Agrobacterium and crown gall disease | |
| Apr. 15 | Plant tissue culture/regeneration/genetic engineering | |
| Apr. 17 | Plant tissue culture/regeneration/genetic engineering | |
| Apr. 20 | plastid development | |
| Apr. 22 | environmentally controlled developmental processes in plants and animals | |
| Apr. 24 | environmentally controlled developmental processes in plants and animals | |
| Apr. 27 | environmentally controlled developmental processes in plants and animals | |
| (EXAM 3, Dr. Berry, to be scheduled during finals week) |
End